KMID : 1199120090330010001
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Korean Diabetes Journal 2009 Volume.33 No. 1 p.1 ~ p.8
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Double Diabetes
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Rhee Sang-Youl
Kim Young-Seol
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Abstract
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Generally, most cases of diabetes mellitus (DM) are classified as either type 1 DM or type 2 DM based on their pathophysiolgic features. However, it is not always possible to classify this disease clearly according to current diagnostic criteria. Recently, the existence of non-typical diabetes has been found in patients with simultaneous features of both type 1 and type 2 DM. In these patients, obvious evidence of insulin resistance, positivity of islet autoantibody, and progressive beta cell loss are observed concurrently. Moreover, this non-typical diabetes that usually occurs among children and adolescents has been defined as ¡¯double diabetes¡¯, and its worldwide incidence has been on the increase as of late. Thus, there has been heightened interest among researchers about this ambiguous condition.
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KEYWORD
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Autoimmunity, Biological Markers, Diabetes Mellitus, Genetic Predisposition to Disease
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